Kim LH, Brandenburg C, Sillitoe RV. Cerebellar motor and non-motor contributions to dystonia pathophysiology and treatment. Dystonia. 2026;5:15082. doi: 10.3389/dyst.2026.15082. Epub 2026 Jul 19. PMID: 42592533.

Brandenburg C, Gill JS, Sillitoe RV. Olivocerebellar circuit development as a substrate for dystonia pathogenesis. Curr Top Dev Biol. 2026;167:379-411. doi: 10.1016/bs.ctdb.2025.11.003. Epub 2025 Dec 11. PMID: 42025367.

Hipolito AGR, Dew MP, Gill JS, Allen JE, Chesky KA, Hull M, Sillitoe RV. Human and mouse cerebellar inhibitory circuits in dystonic crisis and their modulation with therapeutic stimulation. bioRxiv [Preprint]. 2026 Apr 3:2026.04.01.715774. doi: 10.64898/2026.04.01.715774. PMID: 41959326.

Brandenburg C, Srivastava S, Rey Hipolito AG, Lin T, Arenkiel BR, Sillitoe RV. Frequency-dependent cerebellar circuits independently gate social vocalizations and movement. bioRxiv [Preprint]. 2026 Apr 27:2026.02.18.706564. doi: 10.64898/2026.02.18.706564. PMID: 41756943.

Miterko-Myers LN, Peacoe LE, Duraine L, Zuo Z, Sillitoe RV. Cerebellar deep brain stimulation rescues Purkinje cell mitochondrial density in a genetic mouse model of cerebellar ataxia. Brain Res Bull. 2026 Jan;234:111704. doi: 10.1016/j.brainresbull.2025.111704. Epub 2025 Dec 24. PMID: 41453498.

Donofrio SG, Brandenburg C, Brown AM, Lin T, Lu HC, Sillitoe RV. Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice. Elife. 2025 Dec 1;14:RP106273. doi: 10.7554/eLife.106273. PMID: 41324576.

Dhar SS, Ko KP, Jang J, Brown-Abel C, Lin T, Awasthi S, Chen K, Sillitoe RV, Park JI, Lee MG. KMT2D temporally activates neuronal transcriptional factor genes to mediate cerebellar granule cell differentiation. Sci Adv. 2025 Sep 26;11(39):eadu7174. doi: 10.1126/sciadv.adu7174. Epub 2025 Sep 26. PMID: 41004595.

Rodichkin AN, Brown AM, Devabathini P, McGlothan JL, Chen S, Pattammattel A, Chu YS, Lin T, Pontow DD, Abilmouna K, Kapoor R, Hardin SE, Pushkar Y, Sillitoe RV, Guilarte TR. Cerebellar dysfunction in a mouse model of childhood-onset manganese-induced dystonia parkinsonism. Neurobiol Dis. 2025 Nov;216:107115. doi: 10.1016/j.nbd.2025.107115. Epub 2025 Sep 22. PMID: 40992700.

Brandenburg C, Crutcher GW, Romanowski AJ, Donofrio SG, Duraine LR, Owusu-Mensah RNA, Cooper BH, Sugihara I, Blatt GJ, Sillitoe RV, Poulopoulos A. Developmental transformations of Purkinje cells tracked by DNA electrokinetic mobility. Cell Rep Methods. 2025 Sep 15;5(9):101143. doi: 10.1016/j.crmeth.2025.101143. Epub 2025 Aug 26. PMID: 40865536.

Shi G, Miller C, Kuno S, Rey Hipolito AG, El Nagar S, Riboldi GM, Korn M, Tran WC, Wang Z, Ficaro L, Lin T, Spillier Q, Gamallo-Lana B, Jones DR, Snuderl M, Song SC, Mar AC, Joyner AL, Sillitoe RV, Banh RS, Pacold ME. Coenzyme Q headgroup intermediates can ameliorate a mitochondrial encephalopathy. Nature. 2025 Sep;645(8080):466-474. doi: 10.1038/s41586-025-09246-x. Epub 2025 Jul 9. PMID: 40634618.

Brandenburg C, Sillitoe RV. Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor. Neuron. 2025 May 21;113(10):1463-1465. doi: 10.1016/j.neuron.2025.04.016. PMID: 40403701.

Ghiyamihoor F, Peymani P, Perron J, Asemi-Rad A, Marzban M, Mohite A, Ardila K, Aljada B, Marzban A, Toback M, Eltonsy S, Ko JH, Siddiqui TJ, Steele CJ, Kong J, Manto M, MacDonald ME, Gill JS, Sillitoe RV, Balcı F, Beheshti I, Marzban H. Volumetric Changes in Cerebellar Transverse Zones: Age and Sex Effects in Health and Neurological Disorders. Hum Brain Mapp. 2025 Apr 15;46(6):e70214. doi: 10.1002/hbm.70214. PMID: 40241499.

Donofrio SG, Brandenburg C, Brown AM, Lin T, Lu HC, Sillitoe RV. Cerebellar Purkinje cell stripe patterns reveal a differential vulnerability and resistance to cell loss during normal aging in mice. bioRxiv [Preprint]. 2025 Aug 18:2025.01.26.634923. doi: 10.1101/2025.01.26.634923. PMID: 39974902.

Nguyen MX, Brown AM, Lin T, Sillitoe RV, Gill JS. Thalamic deep brain stimulation improves movement in a cerebellar model of lesion-based status dystonicus. Neurotherapeutics. 2025 Mar;22(2):e00543. doi: 10.1016/j.neurot.2025.e00543. Epub 2025 Feb 12. PMID: 39948022.

Salazar Leon LE, Kim LH, Sillitoe RV. Cerebellar deep brain stimulation as a dual-function therapeutic for restoring movement and sleep in dystonic mice. Neurotherapeutics. 2024 Oct;21(6):e00467. doi: 10.1016/j.neurot.2024.e00467. Epub 2024 Oct 23. PMID: 39448336.

van der Heijden ME, Brown AM, Kizek DJ, Sillitoe RV. Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor. Elife. 2024 Jul 29;12:RP91483. doi: 10.7554/eLife.91483. PMID: 39072369.

Mishra I, Feng B, Basu B, Brown AM, Kim LH, Lin T, Raza MA, Moore A, Hahn A, Bailey S, Sharp A, Bournat JC, Poulton C, Kim B, Langsner A, Sathyanesan A, Sillitoe RV, He Y, Chopra AR. The cerebellum modulates thirst. Nat Neurosci. 2024 Sep;27(9):1745-1757. doi: 10.1038/s41593-024-01700-9. Epub 2024 Jul 10. PMID: 38987435.

Nguyen MX, Brown AM, Lin T, Sillitoe RV, Gill JS. Targeting DBS to the centrolateral thalamic nucleus improves movement in a lesion-based model of acquired cerebellar dystonia in mice. bioRxiv [Preprint]. 2024 May 21:2024.05.21.595095. doi: 10.1101/2024.05.21.595095. PMID: 38826430.

Kim LH, Heck DH, Sillitoe RV. Cerebellar Functions Beyond Movement and Learning. Annu Rev Neurosci. 2024 Aug;47(1):145-166. doi: 10.1146/annurev-neuro-100423-104943. Epub 2024 Jul 1. PMID: 38663092.

Salazar Leon LE, Brown AM, Kaku H, Sillitoe RV. Purkinje cell dysfunction causes disrupted sleep in ataxic mice. Dis Model Mech. 2024 Jun 1;17(6):dmm050379. doi: 10.1242/dmm.050379. Epub 2024 Jun 12. PMID: 38563553.

Raghubar KP, Heitzer AM, Malbari F, Gill J, Sillitoe RV, Merrill L, Escalante J, Okcu MF, Aldave G, Meoded A, Kralik S, Davis K, Ma M, Warren EAH, McCurdy MD, Weiner HL, Whitehead W, Scheurer ME, Rodriguez L, Daigle A, Chintagumpala M, Kahalley LS. Adaptive, behavioral, and emotional outcomes following postoperative pediatric cerebellar mutism syndrome in survivors treated for medulloblastoma. J Neurosurg Pediatr. 2024 Mar 29;33(6):516-523. doi: 10.3171/2024.1.PEDS23321. Print 2024 Jun 1. PMID: 38552237.

Gittis AH, Sillitoe RV. Circuit-Specific Deep Brain Stimulation Provides Insights into Movement Control. Annu Rev Neurosci. 2024 Aug;47(1):63-83. doi: 10.1146/annurev-neuro-092823-104810. Epub 2024 Jul 1. PMID: 38424473.

Beckinghausen J, Ortiz-Guzman J, Lin T, Bachman B, Salazar Leon LE, Liu Y, Heck DH, Arenkiel BR, Sillitoe RV. Author Correction: The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus. Commun Biol. 2024 Feb 16;7(1):186. doi: 10.1038/s42003-024-05885-4. PMID: 38365939.

Gill JS, Nguyen MX, Hull M, van der Heijden ME, Nguyen K, Thomas SP, Sillitoe RV. Function and dysfunction of the dystonia network: an exploration of neural circuits that underlie the acquired and isolated dystonias. Dystonia. 2023;2:11805. doi: 10.3389/dyst.2023.11805. Epub 2023 Dec 13. PMID: 38273865.

van der Heijden ME, Sillitoe RV. Cerebellar dysfunction in rodent models with dystonia, tremor, and ataxia. Dystonia. 2023;2:11515. doi: 10.3389/dyst.2023.11515. Epub 2023 Dec 8. PMID: 38105800.

Leon LES, Kim LH, Sillitoe RV. Cerebellar deep brain stimulation as a dual-function therapeutic for restoring movement and sleep in dystonic mice. bioRxiv [Preprint]. 2023 Nov 2:2023.10.30.564790. doi: 10.1101/2023.10.30.564790. PMID: 37961355.

Rey Hipolito AG, van der Heijden ME, Sillitoe RV. Physiology of Dystonia: Animal Studies. Int Rev Neurobiol. 2023;169:163-215. doi: 10.1016/bs.irn.2023.05.004. Epub 2023 May 17. PMID: 37482392.

Salazar Leon LE, Brown AM, Kaku H, Sillitoe RV. Purkinje cell dysfunction causes disrupted sleep in ataxic mice. bioRxiv [Preprint]. 2023 Jul 3:2023.07.03.547586. doi: 10.1101/2023.07.03.547586. PMID: 37461479.

Beckinghausen J, Ortiz-Guzman J, Lin T, Bachman B, Salazar Leon LE, Liu Y, Heck DH, Arenkiel BR, Sillitoe RV. The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus. Commun Biol. 2023 Jul 15;6(1):731. doi: 10.1038/s42003-023-05100-w. PMID: 37454228.

Beckinghausen J, Donofrio SG, Lin T, Miterko LN, White JJ, Lackey EP, Sillitoe RV. Deep Brain Stimulation of the Interposed Cerebellar Nuclei in a Conditional Genetic Mouse Model with Dystonia. Adv Neurobiol. 2023;31:93-117. doi: 10.1007/978-3-031-26220-3_6. PMID: 37338698.

Brown AM, Lackey EP, Salazar Leon LE, Rey Hipolito AG, Beckinghausen J, Lin T, Sillitoe RV. Electromyography as a Method for Distinguishing Dystonia in Mice. Adv Neurobiol. 2023;31:71-91. doi: 10.1007/978-3-031-26220-3_5. PMID: 37338697.

van der Heijden ME, Brown AM, Kizek DJ, Sillitoe RV. Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor. bioRxiv [Preprint]. 2024 Apr 25:2023.05.07.539767. doi: 10.1101/2023.05.07.539767. PMID: 37214855.

van der Heijden ME, Rey Hipolito AG, Kim LH, Kizek DJ, Perez RM, Lin T, Sillitoe RV. Glutamatergic cerebellar neurons differentially contribute to the acquisition of motor and social behaviors. Nat Commun. 2023 May 15;14(1):2771. doi: 10.1038/s41467-023-38475-9. PMID: 37188723.

Salazar Leon LE, Sillitoe RV. Potential interactions between cerebellar dysfunction and sleep disturbances in dystonia. Dystonia. 2022 Oct;1:10691. doi: 10.3389/dyst.2022.10691. Epub 2022 Oct 4. PMID: 37065094.

Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 Mar 15;111(6):915. doi: 10.1016/j.neuron.2023.02.030. PMID: 36924764.

Wong JK, Mayberg HS, Wang DD, Richardson RM, Halpern CH, Krinke L, Arlotti M, Rossi L, Priori A, Marceglia S, Gilron R, Cavanagh JF, Judy JW, Miocinovic S, Devergnas AD, Sillitoe RV, Cernera S, Oehrn CR, Gunduz A, Goodman WK, Petersen EA, Bronte-Stewart H, Raike RS, Malekmohammadi M, Greene D, Heiden P, Tan H, Volkmann J, Voon V, Li L, Sah P, Coyne T, Silburn PA, Kubu CS, Wexler A, Chandler J, Provenza NR, Heilbronner SR, Luciano MS, Rozell CJ, Fox MD, de Hemptinne C, Henderson JM, Sheth SA, Okun MS. Proceedings of the 10th annual deep brain stimulation think tank: Advances in cutting edge technologies, artificial intelligence, neuromodulation, neuroethics, interventional psychiatry, and women in neuromodulation. Front Hum Neurosci. 2023 Jan 27;16:1084782. doi: 10.3389/fnhum.2022.1084782. eCollection 2022. PMID: 36819295.

Leon LES, Sillitoe RV. Disrupted sleep in dystonia depends on cerebellar function but not motor symptoms in mice. bioRxiv [Preprint]. 2023 Feb 10:2023.02.09.527916. doi: 10.1101/2023.02.09.527916. PMID: 36798256.

Coffin SL, Durham MA, Nitschke L, Xhako E, Brown AM, Revelli JP, Villavicencio Gonzalez E, Lin T, Handler HP, Dai Y, Trostle AJ, Wan YW, Liu Z, Sillitoe RV, Orr HT, Zoghbi HY. Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1. Neuron. 2023 Feb 15;111(4):481-492.e8. doi: 10.1016/j.neuron.2022.11.016. Epub 2022 Dec 27. PMID: 36577402.

Zhou J, Van der Heijden ME, Salazar Leon LE, Lin T, Miterko LN, Kizek DJ, Perez RM, Pavešković M, Brown AM, Sillitoe RV. Propranolol Modulates Cerebellar Circuit Activity and Reduces Tremor. Cells. 2022 Dec 1;11(23):3889. doi: 10.3390/cells11233889. PMID: 36497147.

van der Heijden ME, Brown AM, Sillitoe RV. Influence of data sampling methods on the representation of neural spiking activity in vivo. iScience. 2022 Oct 22;25(11):105429. doi: 10.1016/j.isci.2022.105429. eCollection 2022 Nov 18. PMID: 36388953.

Liang JH, Alevy J, Akhanov V, Seo R, Massey CA, Jiang D, Zhou J, Sillitoe RV, Noebels JL, Samuel MA. Kctd7 deficiency induces myoclonic seizures associated with Purkinje cell death and microvascular defects. Dis Model Mech. 2022 Sep 1;15(9):dmm049642. doi: 10.1242/dmm.049642. Epub 2022 Sep 13. PMID: 35972048.

Brown AM, van der Heijden ME, Jinnah HA, Sillitoe RV. Cerebellar Dysfunction as a Source of Dystonic Phenotypes in Mice. Cerebellum. 2023 Aug;22(4):719-729. doi: 10.1007/s12311-022-01441-0. Epub 2022 Jul 12. PMID: 35821365.

Liu Y, McAfee SS, Van Der Heijden ME, Dhamala M, Sillitoe RV, Heck DH. Causal Evidence for a Role of Cerebellar Lobulus Simplex in Prefrontal-Hippocampal Interaction in Spatial Working Memory Decision-Making. Cerebellum. 2022 Oct;21(5):762-775. doi: 10.1007/s12311-022-01383-7. Epub 2022 Feb 26. PMID: 35218525.

McAfee SS, Liu Y, Sillitoe RV, Heck DH. Cerebellar Coordination of Neuronal Communication in Cerebral Cortex. Front Syst Neurosci. 2022 Jan 11;15:781527. doi: 10.3389/fnsys.2021.781527. eCollection 2021. PMID: 35087384.

Van Der Heijden ME, Gill JS, Rey Hipolito AG, Salazar Leon LE, Sillitoe RV. Quantification of Behavioral Deficits in Developing Mice With Dystonic Behaviors. Dystonia. 2022;1:10494. doi: 10.3389/dyst.2022.10494. Epub 2022 Sep 8. PMID: 36960404.

van der Heijden ME, Brown AM, Sillitoe RV. Motor control: Internalizing your place in the world. Curr Biol. 2021 Dec 20;31(24):R1576-R1578. doi: 10.1016/j.cub.2021.10.056. PMID: 34932966.

Stevens SR, van der Heijden ME, Ogawa Y, Lin T, Sillitoe RV, Rasband MN. Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival. J Neurosci. 2022 Jan 5;42(1):2-15. doi: 10.1523/JNEUROSCI.1132-21.2021. Epub 2021 Nov 16. PMID: 34785580.

van der Heijden ME, Lackey EP, Perez R, Ișleyen FS, Brown AM, Donofrio SG, Lin T, Zoghbi HY, Sillitoe RV. Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons. Elife. 2021 Sep 20;10:e68045. doi: 10.7554/eLife.68045. PMID: 34542409.

Kale RP, Nguyen TTL, Price JB, Yates NJ, Walder K, Berk M, Sillitoe RV, Kouzani AZ, Tye SJ. Mood Regulatory Actions of Active and Sham Nucleus Accumbens Deep Brain Stimulation in Antidepressant Resistant Rats. Front Hum Neurosci. 2021 Jul 19;15:644921. doi: 10.3389/fnhum.2021.644921. eCollection 2021. PMID: 34349629.

Karamesinis A, Sillitoe RV, Kouzani AZ. Wearable Peripheral Electrical Stimulation Devices for the Reduction of Essential Tremor: A Review. IEEE Access. 2021;9:80066-80076. doi: 10.1109/access.2021.3084819. Epub 2021 May 28. PMID: 34178561.

van der Heijden ME, Gill JS, Sillitoe RV. Abnormal Cerebellar Development in Autism Spectrum Disorders. Dev Neurosci. 2021;43(3-4):181-190. doi: 10.1159/000515189. Epub 2021 Apr 6. PMID: 33823515.

Miterko LN, Lin T, Zhou J, van der Heijden ME, Beckinghausen J, White JJ, Sillitoe RV. Neuromodulation of the cerebellum rescues movement in a mouse model of ataxia. Nat Commun. 2021 Feb 26;12(1):1295. doi: 10.1038/s41467-021-21417-8. PMID: 33637754.

Achilly NP, He LJ, Kim OA, Ohmae S, Wojaczynski GJ, Lin T, Sillitoe RV, Medina JF, Zoghbi HY. Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice. Elife. 2021 Jan 26;10:e64833. doi: 10.7554/eLife.64833. PMID: 33494858.

Parastarfeizabadi M, Sillitoe RV, Kouzani AZ. Multi-disease Deep Brain Stimulation. IEEE Access. 2020;8:216933-216947. doi: 10.1109/access.2020.3041942. Epub 2020 Dec 2. PMID: 33381359.

van der Heijden ME, Kizek DJ, Perez R, Ruff EK, Ehrlich ME, Sillitoe RV. Abnormal cerebellar function and tremor in a mouse model for non-manifesting partially penetrant dystonia type 6. J Physiol. 2021 Apr;599(7):2037-2054. doi: 10.1113/JP280978. Epub 2021 Jan 9. PMID: 33369735.

Ito-Ishida A, Baker SA, Sillitoe RV, Sun Y, Zhou J, Ono Y, Iwakiri J, Yuzaki M, Zoghbi HY. MeCP2 Levels Regulate the 3D Structure of Heterochromatic Foci in Mouse Neurons. J Neurosci. 2020 Nov 4;40(45):8746-8766. doi: 10.1523/JNEUROSCI.1281-19.2020. Epub 2020 Oct 12. PMID: 33046553.

Zhou J, Brown AM, Lackey EP, Arancillo M, Lin T, Sillitoe RV. Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules defined by distinct pinceau sizes. Elife. 2020 Sep 29;9:e55569. doi: 10.7554/eLife.55569. PMID: 32990595.

van der Heijden ME, Sillitoe RV. Interactions Between Purkinje Cells and Granule Cells Coordinate the Development of Functional Cerebellar Circuits. Neuroscience. 2021 May 10;462:4-21. doi: 10.1016/j.neuroscience.2020.06.010. Epub 2020 Jun 14. PMID: 32554107.

Luck B, Engevik MA, Ganesh BP, Lackey EP, Lin T, Balderas M, Major A, Runge J, Luna RA, Sillitoe RV, Versalovic J. Bifidobacteria shape host neural circuits during postnatal development by promoting synapse formation and microglial function. Sci Rep. 2020 May 8;10(1):7737. doi: 10.1038/s41598-020-64173-3. PMID: 32385412.

Brown AM, White JJ, van der Heijden ME, Zhou J, Lin T, Sillitoe RV. Purkinje cell misfiring generates high-amplitude action tremors that are corrected by cerebellar deep brain stimulation. Elife. 2020 Mar 17;9:e51928. doi: 10.7554/eLife.51928. PMID: 32180549.

Lackey EP, Sillitoe RV. Eph/ephrin Function Contributes to the Patterning of Spinocerebellar Mossy Fibers Into Parasagittal Zones. Front Syst Neurosci. 2020 Feb 13;14:7. doi: 10.3389/fnsys.2020.00007. eCollection 2020. PMID: 32116578.

Lungu C, Ozelius L, Standaert D, Hallett M, Sieber BA, Swanson-Fisher C, Berman BD, Calakos N, Moore JC, Perlmutter JS, Pirio Richardson SE, Saunders-Pullman R, Scheinfeldt L, Sharma N, Sillitoe R, Simonyan K, Starr PA, Taylor A, Vitek J; participants and organizers of the NINDS Workshop on Research Priorities in Dystonia. Defining research priorities in dystonia. Neurology. 2020 Mar 24;94(12):526-537. doi: 10.1212/WNL.0000000000009140. Epub 2020 Feb 25. PMID: 32098856.

Liu Y, Qi S, Thomas F, Correia BL, Taylor AP, Sillitoe RV, Heck DH. Loss of cerebellar function selectively affects intrinsic rhythmicity of eupneic breathing. Biol Open. 2020 Apr 13;9(4):bio048785. doi: 10.1242/bio.048785. PMID: 32086251.

Stay TL, Miterko LN, Arancillo M, Lin T, Sillitoe RV. In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. Dis Model Mech. 2019 Dec 9;13(2):dmm040840. doi: 10.1242/dmm.040840. PMID: 31704708.

Gill JS, Sillitoe RV. Functional Outcomes of Cerebellar Malformations. Front Cell Neurosci. 2019 Oct 4;13:441. doi: 10.3389/fncel.2019.00441. eCollection 2019. PMID: 31636540.

Meng X, McGraw CM, Wang W, Jing J, Yeh SY, Wang L, Lopez J, Brown AM, Lin T, Chen W, Xue M, Sillitoe RV, Jiang X, Zoghbi HY. Neurexophilin4 is a selectively expressed α-neurexin ligand that modulates specific cerebellar synapses and motor functions. Elife. 2019 Sep 16;8:e46773. doi: 10.7554/eLife.46773. PMID: 31524598.

Miterko LN, Baker KB, Beckinghausen J, Bradnam LV, Cheng MY, Cooperrider J, DeLong MR, Gornati SV, Hallett M, Heck DH, Hoebeek FE, Kouzani AZ, Kuo SH, Louis ED, Machado A, Manto M, McCambridge AB, Nitsche MA, Taib NOB, Popa T, Tanaka M, Timmann D, Steinberg GK, Wang EH, Wichmann T, Xie T, Sillitoe RV. Consensus Paper: Experimental Neurostimulation of the Cerebellum. Cerebellum. 2019 Dec;18(6):1064-1097. doi: 10.1007/s12311-019-01041-5. PMID: 31165428.

Kuo SH, Louis ED, Faust PL, Handforth A, Chang SY, Avlar B, Lang EJ, Pan MK, Miterko LN, Brown AM, Sillitoe RV, Anderson CJ, Pulst SM, Gallagher MJ, Lyman KA, Chetkovich DM, Clark LN, Tio M, Tan EK, Elble RJ. Current Opinions and Consensus for Studying Tremor in Animal Models. Cerebellum. 2019 Dec;18(6):1036-1063. doi: 10.1007/s12311-019-01037-1. PMID: 31124049.

McAfee SS, Liu Y, Sillitoe RV, Heck DH. Cerebellar Lobulus Simplex and Crus I Differentially Represent Phase and Phase Difference of Prefrontal Cortical and Hippocampal Oscillations. Cell Rep. 2019 May 21;27(8):2328-2334.e3. doi: 10.1016/j.celrep.2019.04.085. PMID: 31116979.

Sathyanesan A, Zhou J, Scafidi J, Heck DH, Sillitoe RV, Gallo V. Emerging connections between cerebellar development, behaviour and complex brain disorders. Nat Rev Neurosci. 2019 May;20(5):298-313. doi: 10.1038/s41583-019-0152-2. PMID: 30923348.

Miterko LN, White JJ, Lin T, Brown AM, O'Donovan KJ, Sillitoe RV. Persistent motor dysfunction despite homeostatic rescue of cerebellar morphogenesis in the Car8 waddles mutant mouse. Neural Dev. 2019 Mar 12;14(1):6. doi: 10.1186/s13064-019-0130-4. PMID: 30867000.

Brown AM, Arancillo M, Lin T, Catt DR, Zhou J, Lackey EP, Stay TL, Zuo Z, White JJ, Sillitoe RV. Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells. Sci Rep. 2019 Feb 11;9(1):1742. doi: 10.1038/s41598-018-38264-1. PMID: 30742002.

Stay TL, Laurens J, Sillitoe RV, Angelaki DE. Genetically eliminating Purkinje neuron GABAergic neurotransmission increases their response gain to vestibular motion. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3245-3250. doi: 10.1073/pnas.1818819116. Epub 2019 Feb 5. PMID: 30723151.

Miterko LN, Lackey EP, Heck DH, Sillitoe RV. Shaping Diversity Into the Brain's Form and Function. Front Neural Circuits. 2018 Oct 10;12:83. doi: 10.3389/fncir.2018.00083. eCollection 2018. PMID: 30364100.

Lackey EP, Heck DH, Sillitoe RV. Recent advances in understanding the mechanisms of cerebellar granule cell development and function and their contribution to behavior. F1000Res. 2018 Jul 26;7:F1000 Faculty Rev-1142. doi: 10.12688/f1000research.15021.1. eCollection 2018. PMID: 30109024.

Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Isope P, Jörntell H, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Spaeth L, Sugihara I, Valera A, Voogd J, Wylie DR, Ruigrok TJH. Correction to: Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper. Cerebellum. 2018 Oct;17(5):683-684. doi: 10.1007/s12311-018-0959-9. PMID: 29931663.

Apps R, Hawkes R, Aoki S, Bengtsson F, Brown AM, Chen G, Ebner TJ, Isope P, Jörntell H, Lackey EP, Lawrenson C, Lumb B, Schonewille M, Sillitoe RV, Spaeth L, Sugihara I, Valera A, Voogd J, Wylie DR, Ruigrok TJH. Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper [corrected]. Cerebellum. 2018 Oct;17(5):654-682. doi: 10.1007/s12311-018-0952-3. PMID: 29876802.

Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, Sillitoe RV, Chen K, Lee MG. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Mol Cell. 2018 Jun 7;70(5):825-841.e6. doi: 10.1016/j.molcel.2018.04.028. Epub 2018 May 31. PMID: 29861161.

Beckinghausen J, Sillitoe RV. Insights into cerebellar development and connectivity. Neurosci Lett. 2019 Jan 1;688:2-13. doi: 10.1016/j.neulet.2018.05.013. Epub 2018 May 7. PMID: 29746896.

Rousseaux MWC, Tschumperlin T, Lu HC, Lackey EP, Bondar VV, Wan YW, Tan Q, Adamski CJ, Friedrich J, Twaroski K, Chen W, Tolar J, Henzler C, Sharma A, Bajić A, Lin T, Duvick L, Liu Z, Sillitoe RV, Zoghbi HY, Orr HT. ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism. Neuron. 2018 Mar 21;97(6):1235-1243.e5. doi: 10.1016/j.neuron.2018.02.013. Epub 2018 Mar 8. PMID: 29526553.

Parastarfeizabadi M, Kouzani AZ, Beckinghausen J, Lin T, Sillitoe RV. A Programmable Multi-biomarker Neural Sensor for Closed-loop DBS. IEEE Access. 2018;7:230-244. doi: 10.1109/ACCESS.2018.2885336. Epub 2018 Dec 7. PMID: 30976472.

Miterko LN, Sillitoe RV. Climbing Fiber Development Is Impaired in Postnatal Car8 (wdl) Mice. Cerebellum. 2018 Feb;17(1):56-61. doi: 10.1007/s12311-017-0886-1. PMID: 28940157.

Levy SL, White JJ, Lackey EP, Schwartz L, Sillitoe RV. WGA-Alexa Conjugates for Axonal Tracing. Curr Protoc Neurosci. 2017 Apr 10;79:1.28.1-1.28.24. doi: 10.1002/cpns.28. PMID: 28398642.

White JJ, Sillitoe RV. Genetic silencing of olivocerebellar synapses causes dystonia-like behaviour in mice. Nat Commun. 2017 Apr 4;8:14912. doi: 10.1038/ncomms14912. PMID: 28374839.

Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr;49(4):527-536. doi: 10.1038/ng.3808. Epub 2017 Mar 13. PMID: 28288114.

Miterko LN, Sillitoe RV. The pledge, the turn, and the prestige of transient cerebellar alterations in SCA6. J Physiol. 2017 Feb 1;595(3):607-608. doi: 10.1113/JP273301. PMID: 28145007.

Tan Q, Yalamanchili HK, Park J, De Maio A, Lu HC, Wan YW, White JJ, Bondar VV, Sayegh LS, Liu X, Gao Y, Sillitoe RV, Orr HT, Liu Z, Zoghbi HY. Extensive cryptic splicing upon loss of RBM17 and TDP43 in neurodegeneration models. Hum Mol Genet. 2016 Dec 1;25(23):5083-5093. doi: 10.1093/hmg/ddw337. PMID: 28007900.

Hopfner F, Haubenberger D, Galpern WR, Gwinn K, Van't Veer A, White S, Bhatia K, Adler CH, Eidelberg D, Ondo W, Stebbins GT, Tanner CM, Helmich RC, Lenz FA, Sillitoe RV, Vaillancourt D, Vitek JL, Louis ED, Shill HA, Frosch MP, Foroud T, Kuhlenbäumer G, Singleton A, Testa CM, Hallett M, Elble R, Deuschl G. Knowledge gaps and research recommendations for essential tremor. Parkinsonism Relat Disord. 2016 Dec;33:27-35. doi: 10.1016/j.parkreldis.2016.10.002. Epub 2016 Oct 4. PMID: 27769649.

White JJ, Lin T, Brown AM, Arancillo M, Lackey EP, Stay TL, Sillitoe RV. An optimized surgical approach for obtaining stable extracellular single-unit recordings from the cerebellum of head-fixed behaving mice. J Neurosci Methods. 2016 Mar 15;262:21-31. doi: 10.1016/j.jneumeth.2016.01.010. Epub 2016 Jan 14. PMID: 26777474.

White JJ, Arancillo M, King A, Lin T, Miterko LN, Gebre SA, Sillitoe RV. Pathogenesis of severe ataxia and tremor without the typical signs of neurodegeneration. Neurobiol Dis. 2016 Feb;86:86-98. doi: 10.1016/j.nbd.2015.11.008. Epub 2015 Nov 14. PMID: 26586559.

Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Schilling K, Sekerková G, Sillitoe RV, Sotelo C, Uesaka N, Wefers A, Wingate RJ, Hawkes R. Consensus Paper: Cerebellar Development. Cerebellum. 2016 Dec;15(6):789-828. doi: 10.1007/s12311-015-0724-2. PMID: 26439486.

Sillitoe RV. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum. 2016 Feb;15(1):14-17. doi: 10.1007/s12311-015-0712-6. PMID: 26255945.

Lee SK, Sillitoe RV, Silva C, Martina M, Sekerkova G. α-Synuclein expression in the mouse cerebellum is restricted to VGluT1 excitatory terminals and is enriched in unipolar brush cells. Cerebellum. 2015 Oct;14(5):516-27. doi: 10.1007/s12311-015-0673-9. PMID: 25917213.

Tian X, Gala U, Zhang Y, Shang W, Nagarkar Jaiswal S, di Ronza A, Jaiswal M, Yamamoto S, Sandoval H, Duraine L, Sardiello M, Sillitoe RV, Venkatachalam K, Fan H, Bellen HJ, Tong C. A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PLoS Biol. 2015 Mar 26;13(3):e1002103. doi: 10.1371/journal.pbio.1002103. eCollection 2015 Mar. PMID: 25811491.

Gennarino VA, Singh RK, White JJ, De Maio A, Han K, Kim JY, Jafar-Nejad P, di Ronza A, Kang H, Sayegh LS, Cooper TA, Orr HT, Sillitoe RV, Zoghbi HY. Pumilio1 haploinsufficiency leads to SCA1-like neurodegeneration by increasing wild-type Ataxin1 levels. Cell. 2015 Mar 12;160(6):1087-98. doi: 10.1016/j.cell.2015.02.012. PMID: 25768905.

Cerminara NL, Lang EJ, Sillitoe RV, Apps R. Redefining the cerebellar cortex as an assembly of non-uniform Purkinje cell microcircuits. Nat Rev Neurosci. 2015 Feb;16(2):79-93. doi: 10.1038/nrn3886. PMID: 25601779.

Arancillo M, White JJ, Lin T, Stay TL, Sillitoe RV. In vivo analysis of Purkinje cell firing properties during postnatal mouse development. J Neurophysiol. 2015 Jan 15;113(2):578-91. doi: 10.1152/jn.00586.2014. Epub 2014 Oct 29. PMID: 25355961.

Mulherkar S, Uddin MD, Couvillon AD, Sillitoe RV, Tolias KF. The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation. Dev Biol. 2014 Oct 1;394(1):39-53. doi: 10.1016/j.ydbio.2014.08.004. Epub 2014 Aug 14. PMID: 25128586.

White JJ, Arancillo M, Stay TL, George-Jones NA, Levy SL, Heck DH, Sillitoe RV. Cerebellar zonal patterning relies on Purkinje cell neurotransmission. J Neurosci. 2014 Jun 11;34(24):8231-45. doi: 10.1523/JNEUROSCI.0122-14.2014. PMID: 24920627.

Reeber SL, Arancillo M, Sillitoe RV. Bergmann Glia are Patterned into Topographic Molecular Zones in the Developing and Adult Mouse Cerebellum. Cerebellum. 2018 Aug;17(4):392-403. doi: 10.1007/s12311-014-0571-6. PMID: 24906823.

Reeber SL, Otis TS, Sillitoe RV. New roles for the cerebellum in health and disease. Front Syst Neurosci. 2013 Nov 14;7:83. doi: 10.3389/fnsys.2013.00083. eCollection 2013. PMID: 24294192.

Reeber SL, Loeschel CA, Franklin A, Sillitoe RV. Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice. Front Neural Circuits. 2013 Jul 22;7:122. doi: 10.3389/fncir.2013.00122. eCollection 2013. PMID: 23885237.

White JJ, Sillitoe RV. Development of the cerebellum: from gene expression patterns to circuit maps. Wiley Interdiscip Rev Dev Biol. 2013 Jan-Feb;2(1):149-64. doi: 10.1002/wdev.65. Epub 2012 May 7. PMID: 23799634.

White JJ, Sillitoe RV. Postnatal development of cerebellar zones revealed by neurofilament heavy chain protein expression. Front Neuroanat. 2013 May 9;7:9. doi: 10.3389/fnana.2013.00009. eCollection 2013. PMID: 23675325.

Reeber SL, White JJ, George-Jones NA, Sillitoe RV. Architecture and development of olivocerebellar circuit topography. Front Neural Circuits. 2013 Jan 2;6:115. doi: 10.3389/fncir.2012.00115. eCollection 2012. PMID: 23293588.

Sillitoe RV, George-Jones NA, Millen KJ, Hawkes R. Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher. Brain Struct Funct. 2014 Jan;219(1):35-47. doi: 10.1007/s00429-012-0482-6. Epub 2012 Nov 18. PMID: 23160833.

Sakai N, Insolera R, Sillitoe RV, Shi SH, Kaprielian Z. Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation. J Neurosci. 2012 Oct 31;32(44):15377-87. doi: 10.1523/JNEUROSCI.2225-12.2012. PMID: 23115176.

Sillitoe RV. An introduction to journal club in The Cerebellum. Cerebellum. 2012 Dec;11(4):828. doi: 10.1007/s12311-012-0428-9. PMID: 23086707.

White JJ, Reeber SL, Hawkes R, Sillitoe RV. Wholemount immunohistochemistry for revealing complex brain topography. J Vis Exp. 2012 Apr 5;(62):e4042. doi: 10.3791/4042. PMID: 22508094.

Reeber SL, Gebre SA, Filatova N, Sillitoe RV. Revealing neural circuit topography in multi-color. J Vis Exp. 2011 Nov 14;(57):3371. doi: 10.3791/3371. PMID: 22105327.

Strømme P, Dobrenis K, Sillitoe RV, Gulinello M, Ali NF, Davidson C, Micsenyi MC, Stephney G, Ellevog L, Klungland A, Walkley SU. X-linked Angelman-like syndrome caused by Slc9a6 knockout in mice exhibits evidence of endosomal-lysosomal dysfunction. Brain. 2011 Nov;134(Pt 11):3369-83. doi: 10.1093/brain/awr250. Epub 2011 Sep 29. PMID: 21964919.

Oberdick J, Sillitoe RV. Cerebellar zones: history, development, and function. Cerebellum. 2011 Sep;10(3):301-6. doi: 10.1007/s12311-011-0306-x. PMID: 21822545.

Gebre SA, Reeber SL, Sillitoe RV. Parasagittal compartmentation of cerebellar mossy fibers as revealed by the patterned expression of vesicular glutamate transporters VGLUT1 and VGLUT2. Brain Struct Funct. 2012 Apr;217(2):165-80. doi: 10.1007/s00429-011-0339-4. Epub 2011 Aug 4. PMID: 21814870.

Reeber SL, Sillitoe RV. Patterned expression of a cocaine- and amphetamine-regulated transcript peptide reveals complex circuit topography in the rodent cerebellar cortex. J Comp Neurol. 2011 Jun 15;519(9):1781-96. doi: 10.1002/cne.22601. PMID: 21452228.

Reeber SL, Gebre SA, Sillitoe RV. Fluorescence mapping of afferent topography in three dimensions. Brain Struct Funct. 2011 Sep;216(3):159-69. doi: 10.1007/s00429-011-0304-2. Epub 2011 Mar 9. PMID: 21387082.

Sillitoe RV, Vogel MW, Joyner AL. Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. J Neurosci. 2010 Jul 28;30(30):10015-24. doi: 10.1523/JNEUROSCI.0653-10.2010. PMID: 20668186.

Demilly A, Reeber SL, Gebre SA, Sillitoe RV. Neurofilament heavy chain expression reveals a unique parasagittal stripe topography in the mouse cerebellum. Cerebellum. 2011 Sep;10(3):409-21. doi: 10.1007/s12311-010-0156-y. PMID: 20127431.

Sillitoe RV, Stephen D, Lao Z, Joyner AL. Engrailed homeobox genes determine the organization of Purkinje cell sagittal stripe gene expression in the adult cerebellum. J Neurosci. 2008 Nov 19;28(47):12150-62. doi: 10.1523/JNEUROSCI.2059-08.2008. PMID: 19020009.

Sillitoe RV, Chung SH, Fritschy JM, Hoy M, Hawkes R. Golgi cell dendrites are restricted by Purkinje cell stripe boundaries in the adult mouse cerebellar cortex. J Neurosci. 2008 Mar 12;28(11):2820-6. doi: 10.1523/JNEUROSCI.4145-07.2008. PMID: 18337412.

Sillitoe RV, Vogel MW. Desire, disease, and the origins of the dopaminergic system. Schizophr Bull. 2008 Mar;34(2):212-9. doi: 10.1093/schbul/sbm170. Epub 2008 Feb 17. PMID: 18283047.

Sillitoe RV, Joyner AL. Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum. Annu Rev Cell Dev Biol. 2007;23:549-77. doi: 10.1146/annurev.cellbio.23.090506.123237. PMID: 17506688.

Esapa CT, Waite A, Locke M, Benson MA, Kraus M, McIlhinney RA, Sillitoe RV, Beesley PW, Blake DJ. SGCE missense mutations that cause myoclonus-dystonia syndrome impair epsilon-sarcoglycan trafficking to the plasma membrane: modulation by ubiquitination and torsinA. Hum Mol Genet. 2007 Feb 1;16(3):327-42. doi: 10.1093/hmg/ddl472. Epub 2007 Jan 2. PMID: 17200151.

Sillitoe RV, Marzban H, Larouche M, Zahedi S, Affanni J, Hawkes R. Conservation of the architecture of the anterior lobe vermis of the cerebellum across mammalian species. Prog Brain Res. 2005;148:283-97. doi: 10.1016/S0079-6123(04)48022-4. PMID: 15661197.

Benson MA, Sillitoe RV, Blake DJ. Schizophrenia genetics: dysbindin under the microscope. Trends Neurosci. 2004 Sep;27(9):516-9. doi: 10.1016/j.tins.2004.06.004. PMID: 15331232.

Marzban H, Sillitoe RV, Hoy M, Chung SH, Rafuse VF, Hawkes R. Abnormal HNK-1 expression in the cerebellum of an N-CAM null mouse. J Neurocytol. 2004 Jan;33(1):117-30. doi: 10.1023/B:NEUR.0000029652.96456.0d. PMID: 15173636.

Sillitoe RV, Malz CR, Rockland K, Hawkes R. Antigenic compartmentation of the primate and tree shrew cerebellum: a common topography of zebrin II in Macaca mulatta and Tupaia belangeri. J Anat. 2004 Apr;204(4):257-69. doi: 10.1111/j.0021-8782.2004.00282.x. PMID: 15061752.

Sillitoe RV, Künzle H, Hawkes R. Zebrin II compartmentation of the cerebellum in a basal insectivore, the Madagascan hedgehog tenrec Echinops telfairi. J Anat. 2003 Sep;203(3):283-96. doi: 10.1046/j.1469-7580.2003.00216.x. PMID: 14529046.

Sillitoe RV, Benson MA, Blake DJ, Hawkes R. Abnormal dysbindin expression in cerebellar mossy fiber synapses in the mdx mouse model of Duchenne muscular dystrophy. J Neurosci. 2003 Jul 23;23(16):6576-85. doi: 10.1523/JNEUROSCI.23-16-06576.2003. PMID: 12878699.

Sillitoe RV, Hulliger M, Dyck R, Hawkes R. Antigenic compartmentation of the cat cerebellar cortex. Brain Res. 2003 Jul 4;977(1):1-15. doi: 10.1016/s0006-8993(03)02569-1. PMID: 12788507.

Larouche M, Diep C, Sillitoe RV, Hawkes R. Topographical anatomy of the cerebellum in the guinea pig, Cavia porcellus. Brain Res. 2003 Mar 7;965(1-2):159-69. doi: 10.1016/s0006-8993(02)04160-4. PMID: 12591133.

Sarna JR, Larouche M, Marzban H, Sillitoe RV, Rancourt DE, Hawkes R. Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease. J Comp Neurol. 2003 Feb 10;456(3):279-91. doi: 10.1002/cne.10522. PMID: 12528192.

Sanchez M, Sillitoe RV, Attwell PJ, Ivarsson M, Rahman S, Yeo CH, Hawkes R. Compartmentation of the rabbit cerebellar cortex. J Comp Neurol. 2002 Mar 5;444(2):159-73. doi: 10.1002/cne.10144. PMID: 11835188.

Sillitoe RV, Hawkes R. Whole-mount immunohistochemistry: a high-throughput screen for patterning defects in the mouse cerebellum. J Histochem Cytochem. 2002 Feb;50(2):235-44. doi: 10.1177/002215540205000211. PMID: 11799142.